Alzheimer’s Art Quilt Initiative Awards Second Research Grant to the University of Michigan

Alzheimer’s Art Quilt Initiative Awards Second Research Grant to the University of Michigan

(Burton, MI)-- June 9, 2011--The Alzheimer’s Art Quilt Initiative (AAQI) has awarded a grant of $60,160 to the University of Michigan to continue research conducted by Dr. Mi Hee Lim on "Investigation of Small Molecules as Chemical Tools and Potential Therapeutics for Alzheimer's Disease."

This is the 7th of many grants the AAQI plans to award for Alzheimer's research and the second grant to the University of Michigan for Dr. Lim's work.

The AAQI grant money will help fund Dr. Lim’s research group which works to understand the role of metal ions in Alzheimer's disease, especially how metal ions are involved in the formation and aggregation of amyloid plaques in the brain, a hallmark of the disease. Previous reports have suggested that metal interaction with amyloid species are involved in these amyloid plaques coming together. These specific interactions lead to neuronal cell death and the generation of reactive oxygen species, which initiates oxidative stress. They plan to develop small molecules as chemical tools that can be used to study the interaction between amyloid beta plaques and metal ions. Not only will they be working on breaking up the plaque into smaller pieces (so that it can be removed from the brain), but they will also be focusing on preventing the amyloid plaque deposits from occurring.

Dr Lim is Research Assistant Professor at the Life Sciences Institute and Assistant Professor of Chemistry and a Research Assistant Professor at the University of Michigan. She received her training at the Ewha Woman’s University in Seoul, Korea (BS in Chemistry; MS in Molecular Life Sciences), Massachusetts Institute of Technology (PhD in Chemistry) and did post-doctoral work at California Institute of Technology (Chemistry).

The Alzheimer's Art Quilt Initiative ( is a national, grassroots organization whose mission is to raise awareness and fund research. It auctions and sells donated quilts through the Priority: Alzheimer's Quilt project. The Alzheimer's Art Quilt Initiative has raised more than $552,000 since January 2006. Ami Simms of Flint, Michigan is the founder and executive director of the AAQI, a 501(c)(3) nonprofit corporation operated entirely by volunteers. She is a quilter. Her mother had Alzheimer's.

For more information on the AAQI or to make a donation, contact Ami Simms at 810-637-5586 (9 a.m. – 3 p.m. Eastern), or


Ami Simms
Founder and Executive Director
Alzheimer's Art Quilt Initiative
1200 Creekwood Trail
Burton, MI 48509
(810) 637-5586


The images below are available for publication, courtesy University of Michigan.
From left to right: Dr. Alan R. Saltiel (Director, Life Sciences Institute, University of Michigan), Dr. Mi Hee Lim (Principal Investigator), Ami Simms (AAQI Founder & Executive Director), and Dr. Jung-Suk Choi (Postdoctoral Fellow)

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